JW 642


CAS No. : 1416133-89-5

1416133-89-5
Price and Availability of CAS No. : 1416133-89-5
Size Price Stock
5mg $45 In-stock
10mg $70 In-stock
50mg $250 In-stock
100mg $450 In-stock
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Cat. No. : HY-12332
M.Wt: 462.39
Formula: C21H20F6N2O3
Purity: >98 %
Solubility: DMSO : ≥ 100 mg/mL (216.27 mM)
Introduction of 1416133-89-5 :

JW 642 is a potent inhibitor of monoacylglycerol lipase (MAGL) that displays IC50 values of 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively. IC50 value: 7.6/14/3.7 nM(mouse/rat/human MAGL) [1] Target: MAGL inhibitor JW 642 is selective for MAGL, requiring much higher concentrations to effectively inhibit fatty acid amide hydrolase activity (IC50s = 31, 14, and 20.6 μM for mouse, rat, and human brain membranes, respectively).

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