JD-5037
CAS No. : 1392116-14-1
| Size | Price | Stock |
|---|---|---|
| 5mg | $108 | In-stock |
| 10mg | $175 | In-stock |
| 50mg | $550 | In-stock |
| 100mg | $828 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-18697 |
| M.Wt: | 572.51 |
| Formula: | C27H27Cl2N5O3S |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (436.67 mM; Need ultrasonic) |
JD-5037 is a potent CB1R antagonist with an IC50 of 1.5 nM. IC50 & Target: IC50: 1.5 nM (CB1R)[1] In Vivo: JD5037 (3 mg/kg/d, i.p.) induces equal reductions in body weight, attenuates the HFD-induced hyperglycemia, and reduces the HFD-induced hepatic injury and steatosis in obese Magel2-null mice[2]. JD5037 (3 mg/kg/day, p.o.) significantly reduces the size of tumors and abrogates the tumor in DEN-treated mice. JD5037 attenuates the AEA levels in HCC samples from mice[3].
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