THK-5117


CAS No. : 1374107-54-6

1374107-54-6
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Cat. No. : HY-101182
M.Wt: 326.36
Formula: C19H19FN2O2
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1374107-54-6 :

THK-5117, an arylquinoline derivative, displays high binding affinity to tau fibrils with a Ki of 10.5 nM. THK-5117 has high binding affinity to tau protein aggregates and tau-rich Alzheimer disease (AD)  brain homogenates. 18F-THK-5117 has the potential to act as a tau imaging PET probe[1].

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