ML-210


CAS No. : 1360705-96-9

1360705-96-9
Price and Availability of CAS No. : 1360705-96-9
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Cat. No. : HY-100003
M.Wt: 475.32
Formula: C22H20Cl2N4O4
Purity: >98 %
Storage: at 20℃ 2 years
Solubility: 10 mM in DMSO
Introduction of 1360705-96-9 :

ML-210,the most potent compound in the nitroisoxazole series, is a selective covalent inhibitor of glutathione peroxidase 4 (GPX4) by binding the selenocysteine residue[1]. ML-210 has IC50s of 71 nM, 272 nM and 107nM for BJeLR (HRASV12), BJeH-LT (without HRASV12) and DRD cell lines, respectively[2]. IC50 & Target: Glutathione Peroxidase 4 (GPX4)[1]

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