CP21R7
CAS No. : 125314-13-8
(Synonyms: CP21)
| Size | Price | Stock |
|---|---|---|
| 1mg | $72 | In-stock |
| 5mg | $132 | In-stock |
| 10mg | $192 | In-stock |
| 25mg | $348 | In-stock |
| 50mg | $588 | In-stock |
| 100mg | $948 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-100207 |
| M.Wt: | 317.34 |
| Formula: | C19H15N3O2 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 32 mg/mL (100.84 mM) |
CP21R7 is potent GSK-3β inhibitor, with an IC50 of 1.8 nM; CP21R7 also shows inhibitory activitiy against PKCα, with an IC50 of 1900 nM. IC50 & Target: IC50: 1.8 nM (GSK-3β), 1900 nM (PKCα)[1] In Vitro: CP21R7 (Compound 9) is a selective inhibitor of GSK-3β, with an IC50 of 1.8 nM; the IC50 of CP21R7 against PKCα is 1900 nM[1]. CP21R7 (CP21, 3 μM) potently activates canonical Wnt signaling with highest activity. CP21 significantly increases total levels of intracellular β-catenin. CP21 combined with BMP4 induces commitment of hPSCs towards mesoderm[2].
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