JNJ-31020028
CAS No. : 1094873-14-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $90 | In-stock |
| 10mg | $144 | In-stock |
| 50mg | $450 | In-stock |
| 100mg | $730 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-14450 |
| M.Wt: | 565.68 |
| Formula: | C34H36FN5O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 21.5 mg/mL (38.01 mM; Need ultrasonic and warming) |
JNJ-31020028 is a selective and brain penetrant antagonist of neuropeptide Y Y2 receptor with pIC50 values of 8.07 and 8.22 for human and rat Y2 receptor, respectively. JNJ-31020028 can be used for the research of nervous disease[1]. In Vitro: JNJ-31020028 (0-10 μM) selectively binds with hY2 , rY2 and mY2 with pIC50 values of 8.07, 8.22 and 8.21, respectively[1]. JNJ-31020028 (0.1 nM-10 μM; 1 hour) inhibits PYY-induced calcium response with a pKB value of 8.04[1]. In Vivo: JNJ-31020028 (0-20 mg/kg; s.c. once) affects the level of plasma corticosterone and refeeding result in stressed animals[1].
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