TPO agonist 1
CAS No. : 1033040-23-1
| Size | Price | Stock |
|---|---|---|
| 2mg | $120 | In-stock |
| 5mg | $168 | In-stock |
| 10mg | $264 | In-stock |
| 50mg | $900 | In-stock |
| 100mg | $1440 | In-stock |
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| Cat. No. : | HY-100380 |
| M.Wt: | 466.49 |
| Formula: | C25H22N8O2 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 36 mg/mL (77.17 mM) |
TPO agonist 1 is a thrombopoietin (TPO) agonist extracted from patent WO2008134338A1, compound TPO mimetic. It would be useful as promoters of thrombopoiesis and megakaryocytopoiesis to treat thrombocytopenia[1]. IC50 & Target: TPO receptor[1] In Vivo: The thrombopoietin (TPO) receptor agonists are novel treatments for patients with chronic ITP aimed at increasing platelet production through interactions with the TPO receptor on megakaryocytes, and can increases platelet counts, decrease bleeding events and reduce the need for adjunctive or rescue treatments. The TPO receptor agonists are well-tolerated, though uncertainty remains regarding the risk of thromboembolism and bone marrow fibrosis[2].
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